Treatment of Partial-Thickness Burn Wounds with Combined Advanced Therapies: Cultured Allogenic Keratinocyte and Epidermal Growth Factor
نویسندگان
چکیده
Background: Cultured allogenic keratinocyte (CAK) and epidermal growth factor (EGF) are commonly used biological treatments for partial-thickness burn wounds. A comparative study was conducted on whether the combination therapy of CAK EGF promotes wound healing.Methods: From January 2020 to March 2021, 73 patients who visited hospital with burns were enrolled in study. Patients treated (Kaloderm) (n=20), (Easyef) (n=17), CAK+EGF (n=24). Wound healing rate, time heal, factors affecting (age, sex, underlying disease, mode injury, location initial size), scarring comparatively analyzed.Results: The rate 20 days 85% (17/20) group, 88% (15/17) 92% (22/24) group. average 11.0±6.0 days, group taking 12.6±5.5 11.5±6.0 9.0±6.3 days. received treatment had higher hazard than without (hazard ratio, 2.078; 95% confidence interval, 1.021–4.228). Smaller size <5 cm2 2.869; 1.426–5.773) associated complete healing. Though statistically insignificant (P=0.218), less scars occurred group.Conclusion: Combination
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ژورنال
عنوان ژورنال: Journal of wound management and research
سال: 2023
ISSN: ['2586-0402', '2586-0410']
DOI: https://doi.org/10.22467/jwmr.2022.02187